Driving groundbreaking research. Improving lives.

Helping people with an MPN live a better quality of life as we work toward answers to prevention, progression and a cure for polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF) – blood cancers collectively known as myeloproliferative neoplasms.

MPNRF By the Numbers

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What is Primary Myelofibrosis (MF)?

Primary Myelofibrosis (MF)

PMF is a chronic blood cancer in which excessive scar tissue forms in the bone marrow and impairs its ability to produce normal blood cells.

Learn more about MF

What is Essential Thrombocythemia (ET)?

Essential Thrombocythemia (ET)

Most commonly diagnosed in women over the age of 50, ET is associated with a proliferation of platelet precursors in the bone marrow and complications frequently include blood clotting and/or bleeding.

Learn more about ET

What is Polycythemia Vera (PV)

Polycythemia Vera (PV)

The disease is most common in men over the age of 60, but anyone can develop PV. PV patients typically experience an elevated red blood cell count, an elevated platelet count and an enlarged spleen, especially over time.

Learn more about PV

Recent News

  • Protected: Blood Cancer Awareness Month 2022

    MPN NEWS | August 9, 2022

    There is no excerpt because this is a protected post.


    Advances of Note From EHA2022 

    MPN NEWS | July 29, 2022

    The European Hematology Association’s EHA2022 Congress in Vienna brought together global research leaders, practitioners, and other participants in June to share the latest advances in hematology. Among those on MPNs were the following:   “ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFa axis mediated inflammation and fibrocyte generation in myeloproliferative neoplasms”   This study illustrated the crucial role… Read More »Advances of Note From EHA2022 


    MPN Stem Cells Suffer From ‘Corrupting Influence’

    MPN NEWS | July 29, 2022

    Interferon has been shown to be very effective in some patients with MPNs, often alleviating their fatigue, enlarged spleen, and other symptoms. Some patients show important additional benefits, such as molecular response, even long-term remission and the delay of disease progression. For others with ET, PV or MF, interferon has no measurable effect. As part… Read More »MPN Stem Cells Suffer From ‘Corrupting Influence’

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    Julie and her family joined team MPN and created HikeMF to join the fight against MPNs.

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    Under the Microscope