News & articles

Philadelphia-negative myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF), are hematologic malignancies characterized by the abnormal proliferation of blood cells in the bone marrow. MPNs cause significant morbidity in the form of burdensome symptoms, potentially fatal cardiovascular complications, progression to more aggressive disease, and over time, can evolve to… Read More »Current and emerging therapies

Dr. Ruben Mesa on his move to Wake Forest Baptist Comprehensive Cancer Center MPN patients are asking about your recent move from MD Anderson to Levine Cancer Center/Wake Forest Health. How would you describe the impact of your move?   I am excited to be joining two wonderful MPN teams already well established – in Charlotte… Read More »Q&A with Dr. Ruben Mesa

Just Published NUTRIENT Trial: Mediterranean Diet Intervention in MPNs The Mediterranean diet has long been associated with disease fighting anti-inflammatory benefits. In recent years, it has become a standard component of care for the prevention and management of many chronic conditions, such as cardiovascular disease. It has not yet entered the treatment algorithm for MPNs,… Read More »Just Published NUTRIENT Trial: Mediterranean Diet Intervention in MPNs

Advancing Research: Targeting the JAK2V617F Hematopoietic Stem Cell Through Integrins-Based Combination Early in her career, as a veterinarian, Shinobu Matsuura, DVM, PhD, remembers a debilitating case of aplastic anemia in a young German shepherd. It pulled on her heart strings and solidified her belief that bone marrow is the most important organ in the body. … Read More »Targeting the JAK2V617F hematopoietic stem cell through integrins-based combination

MPNs More Visible Than Ever at ASCO 2023  Recognized as the premier educational and scientific event for the greater oncology community, MPN presentations and posters were more prominent than ever at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.   MPNRF’s presence at ASCO was all encompassing. Our team was there to… Read More »2023 ASCO Annual Meeting MPN Highlights

2023 European Hematology Congress MPN Highlights The European Hematology Association (EHA) Congress 2023 in Frankfurt, Germany in June, brought more than 10,000 participants together, with a much higher representation of MPN research and clinical advances than in previous years.   In one major session, presentations by leaders of an MPN specialized working group represented the work… Read More »2023 European Hematology Congress MPN Highlights

It’s not something most of us think about, but including in your will a gift to a cause you care about, like MPN Research Foundation, has personal benefits for you long before your assets are distributed as you wish.  Four benefits you can collect on now: Lessening anxiety. Thinking and planning ahead can make it… Read More »Benefits of Giving to MPN Research in Your Will

While the Annual Meeting of the American Association for Cancer Research (AACR), held in April 2023, focused a great deal on understanding, decoding, and advocating for cancer health equity and inclusion, there were also significant scientific take-aways important to the treatment of MPNs.  One presentation by Haris Ali, MD, City of Hope Comprehensive Cancer Center,… Read More »AACR Annual Meeting MPN Highlights

Advancing Research: Preventing Blood Clots in MPNs Blood clots, heart attacks, and strokes are leading causes of death or disability in patients with MPNs, typically as a result of elevated platelets and/or red blood cells. Dr. Joan Beckman’s lab at the University of Minnesota is currently working to determine whether growth-arrest-specific 6 protein (Gas6) contributes… Read More »Preventing Blood Clots in MPNs

Today’s Understanding of MPNs: Article Reviews in ASH Journal Blood The world’s current understanding of myeloproliferative neoplasms (MPNs) is showcased in a review of MPN articles published in the April 2023 issue of the American Society of Hematology (ASH) journal Blood (Vol 141 Number 16: April 20, 2023).  The articles describe the latest advances in the field… Read More »Today’s Understanding of MPNs: Review Articles in ASH Journal Blood