John Crispino, PhD, MBA


John Crispino, PhD, MBA

John Crispino, PhD, MBA, is the Robert I. Lurie, MD and Lora S. Lurie Professor of Medicine at Northwestern University, the Vice Chief of Research in the Division of Hematology/Oncology, and the Associate Director of Education and Training for the Robert H. Lurie Comprehensive Cancer Center. Dr. Crispino received his PhD from the Massachusetts Institute of Technology for research on the mechanisms of RNA splicing performed in the laboratory of Dr. Phillip Sharp, Nobel Laureate in Physiology or Medicine. He then performed post-doctoral hematology research at Harvard Medical School and Children’s Hospital of Boston with Dr. Stuart Orkin before moving to Chicago in 2000. Over the past 17 years, Dr. Crispino and members of his laboratory have made many important contributions to improve our understanding of the mechanisms of normal and malignant blood development. Currently, his research is focused on the biology of red blood cells and megakaryocytes, the characterization of genetic changes that lead to Myeloproliferative Neoplasms and Acute Myeloid Leukemia, and the development of novel, targeted therapies for patients with these malignancies. He has authored over 100 publications, with recent papers in Nature Medicine, Cell, Cell Stem Cell, Molecular Cell, Journal of Clinical Investigation, and Blood. Dr. Crispino is a former scholar of the American Society of Hematology and the Leukemia and Lymphoma Society and was named the 2017 Researcher of the year by the Illinois Chapter of the Leukemia and Lymphoma Society. He is on the editorial boards of Leukemia and Blood Cancer Journal and reviews grants for the NIH, the Leukemia and Lymphoma Society, and the American Society of Hematology.

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