Shaoguang Li

Meet Shaoguang Li

Shaoguang Li MPN Researcher

What brought you to MPN research?

My laboratory has a history of studying human chronic myeloid leukemia (CML). Pathologically, CML is similar to MPNs including PV. MPNs have a risk of developing acute leukemia. Thus, I became interested in studying MPNs. 

What labs have you worked in?

I did my postdoctoral research in Dr. Richard Van Etten’s lab at Harvard Medical School between 1996-2001. I began my independent research career at The Jackson Laboratory, and later moved my lab to University of Massachusetts Medical School until now. 

How will your current research help MPN patients?

My research focuses on identifying novel target genes in PV-initiating cells for developing curative therapeutic strategies for MPNs. We have discovered some promising candidate genes to be further tested functionally.

What role does MPNRF play in the progress of your research?

MPNRF plays a vital role in supporting my MPN research. I am impressed with the ability of the foundation to identify good projects and then find ways to support them. I truly believe that MPNRF will lead MPN research and find cure for these diseases. 

Let's pretend it's 50 years from now, and we're looking back on this period of time. What are people going to say MPN researchers accomplished?

I believe people would say that because of the hard work by MPN researchers, we have brought a good quality of lives to patients and have found curative therapies for the majority of MPN patients, if not for all of them. 

What obstacles do researchers face in pursuing their research goals?

Frankly, the most difficult obstacles we‘re facing are insufficient NIH funding and seemingly endless “struggle” to maintain our jobs for doing what we’re wanting to do: helping to develop new and effective therapies for patients with MPNs or other diseases. 

What do you like to do when not working in the lab?

I’ve been trying to improve my opera singing skill to a “professional” level, so that I could sing for patients whom my MPN research has affected.

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