2014 Lei Ding
Columbia University Medical Center
Hematopoietic stem cell niche in myelofibrosis
Fibrosis and the Bone Marrow Niche
We know that a change in the stem cells that give rise to all blood cell types can contribute to Leukemia and MPNs. We don't know how these changes occur. In genetic tracing experiments, this researcher and his group will probe changes in the cells with MF and perform an expression profiling study to identify potential novel therapeutic targets for myelofibrosis.