Celebrating the discovery of mutated CALR
MPN Research Foundation is proud to celebrate the 10-year anniversary of the identification of CALR as a common driver of MPNs. We funded early work that discovered this MPN driver mutation. Learn more >
MPNRF by the numbers
Total donated dollars
invested in research
$ 0 M
Researchers supported
0
Countries with
supported research
0
Projects funded
0

What is
essential
thrombocythemia
(ET)?

Essential Thrombocythemia (ET)

Most commonly diagnosed in women over the age of 50, ET is associated with a proliferation of platelet precursors in the bone marrow and complications frequently include blood clotting and/or bleeding.

Learn more about ET

What is
polycythemia vera
(PV)?

Polycythemia vera (PV)

The disease is most common in men over the age of 60, but anyone can develop PV. PV patients typically experience an elevated red blood cell count, an elevated platelet count and an enlarged spleen, especially over time.

Learn more about PV

What is
myelofibrosis
(MF)?

Myelofibrosis (MF)

MF is a chronic blood cancer in which excessive scar tissue forms in the bone marrow and impairs its ability to produce normal blood cells.

Learn more about MF
Patients, clinicians, researchers, and the biotech and pharma industries all have critical roles to play in advancing MPN research and are all important members of the MPNRF community.
Connect with us to be part of our coordinated effort to find new treatments — and eventually cures — for MPNs.

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and Caregivers

Every patient experience is unique and provides new clues for researchers and clinicians.

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and
Clinicians

In our 24-year history, MPNRF has contributed to some of the most influential MPN research discoveries.

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Industry
and
Biopharma

Engage with us to ensure that new therapies have the maximum impact on patient outcomes and quality of life.

MPN ROUNDTABLE™

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Julie and her family joined team MPN and created HikeMF to join the fight against MPNs.

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Recent news

  • Severe Itching Remains an MPN Research Challenge

    MPN NEWS | April 23, 2024

    This spring allergy season, if you suffer from the distraction and annoyance of itchy eyes or nose, imagine that intense itch across your entire body – every day of the year. That’s what many people living with polycythemia vera (PV) and other MPNs experience. Severe, recurrent MPN-related pruritus (the condition of itching) can have a… Read More »Severe Itching Remains an MPN Research Challenge

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    Reducing Blasts in MPNs

    MPN NEWS | April 23, 2024

    The transformation of MPNs to blast-phase (BP) is generally associated with poorer long-term survival. A recently published study in Blood Advances looked at outcomes of intensive and non-intensive blast reduction strategies in both the blast phase and accelerated phase of MPNs. Blasts are immature white blood cells found naturally in the bone marrow and circulating… Read More »Reducing Blasts in MPNs

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    Belinda Guo

    MPN NEWS | April 23, 2024

    Profile: Belinda Guo, PhD, University of Western Australia One of the impacts MPNRF has on the global MPN community is the support of researchers whose work in other hematologic areas brings different approaches and potential new findings to the study of MPNs. That was true of Dr. Belinda Guo when she received her first funding… Read More »Belinda Guo

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